Who shouldn’t take a Grip test?

Great that you are thinking of doing a Grip test! It’s the first step towards knowing more about your fertility and hormones. Having said that - a Grip test is unfortunately not useful for everyone. If you are thinking about purchasing one of our kits, then please consider if you are among the few who should not get a test.


Even if you belong to one of these categories, of course we welcome you to get a test - as long as you understand that we won’t be able to interpret all results properly.



First of all, what do we test at Grip?

We test for four of the most common and significant fertility issues in females. This includes your risk of: PCOS, an under- or overactive thyroid, blocked fallopian tubes (based on an old Chlamydia infection), early menopause.


To assess these risks, we test the following:

Testosterone, LH, TSH, Chlamydia antibodies, and AMH. You can read about all hormones on our science page.


If you are younger than 23 or older than 43 years old

At Grip we keep up with medical science, but unfortunately medical science is not always clear about everything either. AMH values help us predict your risks of early menopause, however we know that for women under 23 years old and women above 43 years old, the predictive value is weaker (1).


Therefore we would like to recommend the following:

  • If you are under 23 years old, it might be worthwhile waiting a little bit longer before testing. We advise you to keep track of your cycles.

  • If you are 42 or 43 years old, the predictive value of AMH is slightly less accurate, since the cut-off for early menopause is considered to be 45 years old. We recommend you take this into consideration when ordering a Grip test.

  • If you are over 43 years old, we only recommend testing if you are suspecting that you are entering menopause.


If you have been trying to conceive for over 9 or 10 months

Grip was founded on the odd idea that women need to try to conceive for at least a year before they are eligible for further testing in general practice. At Grip we believe knowledge is power and we encourage transparency.


Of course we are more than happy to get you tested if you are trying to conceive at the moment, but remember that your GP might be able to test you for free within the next few months. Find out about tips on trying to conceive in one of our blogs: Grip 101: getting pregnant and Lifestyle and fertility.


If you have been diagnosed with PCOS

Since PCOS is one of the main diagnoses we assess in a Grip test, having the diagnosis impacts the usefulness for testing. Additionally, in PCOS over-maturing follicles will give off excess AMH and thus give a false indication of your ovarian reserve. This leaves us with two remaining tests: your thyroid function and Chlamydia antibodies, which only give limited insight into your fertility.


Want more information on PCOS? Read our blogs PCOS and fertility & PCOS isn't just a fertility problem.


If you have been diagnosed with endometriosis.

Several hormones are affected in endometriosis (2): LH, testosterone and AMH may be decreased. Research performed on the predictive value of AMH for early menopause has only been done on women without endometriosis (3). We also know that AMH often declines faster among women with this condition. Unfortunately, those two things combined mean we can’t say anything about your ovarian reserve.


If you are taking specific medication

Some medication may impact your test results. For example Levothyroxine (thyroid medication), certain steroids (hydrocortisone), Lithium (mood stabiliser), or Isotretinoin (for acne) can all alter outcomes. Remember that some herbs or alternative treatment may also influence the test!


Grip has investigated many different types of medications, to check for possible interactions, and we continue to do so. If you are on any medication or alternative treatment, we recommend you to always note this when filling out our online quiz, or check with us before ordering a Grip test.




Have your questions not been answered? Or are you still in doubt about whether or not to get a Grip test? Contact us at heygrip.co.uk and we will have one of our doctors look into it.



References:

  1. Tehrani, F. R., Shakeri, N., Solaymani-Dodaran, M., & Azizi, F. (2011). Predicting age at menopause from serum antimüllerian hormone concentration. Menopause (New York, N.Y.), 18(7), 766–770. https://doi.org/10.1097/gme.0b013e318205e2ac

  2. Dinsdale, NL, Crespi, BJ. Endometriosis and polycystic ovary syndrome are diametric disorders. Evol Appl. 2021; 14: 1693– 1715. https://doi.org/10.1111/eva.13244

  3. Desongnis, S., Robin, G., Dewailly, D., Pigny, P., & Catteau-Jonard, S. (2021). AMH assessment five or more years after an initially low AMH level. European journal of obstetrics, gynecology, and reproductive biology, 256, 70–74. https://doi.org/10.1016/j.ejogrb.2020.10.053